A large number of laboratory and clinical research data show that the immune response of HPV host plays a very important role in controlling HPV infection and related diseases. Low immune status to HPV is prevalent in patients with HPV precancerous lesions and cervical cancer. HPV preventive vaccine mainly uses synthetic L1 late protein virus like particles with natural spatial structure as the target antigen to induce the body to produce high titer serum neutralizing antibodies to neutralize the virus and assist tumor specific killing T lymphocytes to eliminate virus infection.

The great contribution of Pasteur, known as the father of vaccines, is that he selects pathogenic microorganisms with strong immunogenicity to be cultured, inactivated by physical or chemical methods, and then purified. Inactivated vaccines generally use strong strains, but attenuated weak strains also have good immunogenicity, such as the inactivated polio vaccine produced with Sabin attenuated strains. Live attenuated vaccine is a kind of vaccine which is made of live microorganisms with highly weakened virulence or basically non-toxic selected from nature by means of artificial directional mutation, and is used to inoculate people to prevent infectious diseases.

Overview of current new modern biopharmaceutical technology

Characteristics of biotechnology drugs: