Molecular therapy nuclear acids: effects of long-term culture on biological characteristics and RNA profile of human bone marrow mesenchymal stem cells

Scientists use embryonic stem cells to create "in vitro follicles"

The use of hydroxychloroquine has long been associated with cardiotoxicity, ophthalmic and gastrointestinal complications. This new study suggests that there may be additional side effects that may affect the patient population. For example, mutations caused by DNA damage are the cause of many chronic diseases, including cancer. Besaratinia said, "this drug can induce gene mutations, which means that we must carefully evaluate the risks and benefits of its use, especially in the context of clinical trials."

The biopharmaceutical specialty cultivates high-tech applied talents who master the basic theories, basic skills and process engineering of modern biological science and biotechnology, have the professional quality of biopharmaceutical technology, and can be engaged in drug production, management and technology research and development. Students are required to master the basic theory, basic knowledge and basic skills in the field of biopharmaceutical; Master the process and equipment design method of drug production device; Have the preliminary ability to research, develop and design new resources, new products and new processes of drugs; Have the ability to design and implement experiments, summarize and analyze experimental results and write papers; Be familiar with the national guidelines, policies and regulations on pharmaceutical production, design, research and development, environmental protection, etc; Proficient in a foreign language, with the ability of listening, speaking, reading and writing; Master the basic methods of document retrieval and data query, and have certain scientific research and practical work ability.

Biopharmaceutical is the use of biotechnology to produce natural active substances in living organisms. Its effective ingredients are usually some bioactive proteins, DNA, viruses, cells or tissues, etc. the administration method is direct tissue injection. The preparation of drugs is very dependent on the direct culture of biological tissues / cells and usually cannot be accurately replicated.